Posterior leaflet extension with glutaraldehyde-treated autologous pericardial patch for atrial mitral regurgitatio

Not Applicable

Recruiting

• Conditions: Atrial mitral regurgitation

• Registration Number: JPRN-jRCTs031210021
• Lead Sponsor: Sakamoto Hiroaki

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-04-07
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

1) Patients with atrial MR of moderate (grade 2) or greater
2) Patients with heart failure symptoms of NYHA functional classification II or higher due to significant atrial MR even after optimal medications and have indication of surgery
3) Men and women over 20 years old
4) Patients with written informed consent

Exclusion Criteria

1) Patients with the following findings unsuitable for reconstrucion of mitral valve with autologous pericardial patch
1. Moderate or greater mitral valve stenosis
2. Severe mitral valve calcification
3. Severe pericardial calcification
2) Patients with severe left ventricular dysfunction (left ventricular ejection fraction <30%)
3) Patients with infections endocarditis
4) Patients with acute myocardial infarction within 30 days before surgery
5) Patients with severe lung disease (emphysema, chronic obstructive pulmonary disease, pulmonary fibrosis)
6) Patients with severe liver cirrhosis
7) Patients with a history of pericarditis
8) Women who are pregnant or may become pregnant
9) Patients who are judged inappropriate by the researcher

Study & Design

• Study Type: Interventional
• Study Design: Not specified