Syndrome of Fever Associated With Bleeding of Chinese and Western Medicine Diagnosis and Treatment of Infectious Diseases Plans and Severe Clinical Treatment Research
Trial Snapshot
- Phase
- Phase 2
- Sponsor
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- Mortality
Study Overview
Brief Summary
To meet eligibility criteria, this study and informed consent of the syndrome of fever associated with bleeding of infectious diseases, severe patients to carry out multicenter, practical randomized controlled clinical research, to compare the curative effect of western medicine, combining Chinese and western medicine treatment, and security, and pathogenesis of TCM and syndrome, severe immune related factor and syndrome type of traditional Chinese medicine, Chinese medicine prescriptions mechanism research.
Detailed Description
Randomized method: using large sample, central randomized, parallel comparison of Chinese and western medicine and western medicine group.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Factorial
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Viral diseases, such as dengue fever, kidney of hemorrhagic fever, such as xinjiang hemorrhagic fever; Or clinical has fever associated with bleeding as the main performance, and confirmed as the new emergent infectious diseases
Exclusion Criteria
- •Diagnosed with flu, hand, foot and mouth disease, viral hepatitis (except the carrier), liver cirrhosis after hepatitis, AIDS, rabies, encephalitis, polio, measles, German measles, chickenpox, herpes, infectious mononucleosis, infectious atypical pneumonia
Arms & Interventions
TCM and Western Medicine
TCM and Western Medicine:First Infectious diseases soup recipe,every time a dose,Two times a day;Ribavirin 10-15mg per kg every time Western Medicine：Ribavirin 10-15mg per kg every time
Intervention: Western Medicine (Drug)
TCM and Western Medicine
TCM and Western Medicine:First Infectious diseases soup recipe,every time a dose,Two times a day;Ribavirin 10-15mg per kg every time Western Medicine：Ribavirin 10-15mg per kg every time
Intervention: TCM and Western Medicine (Drug)
Western Medicine
Western Medicine：Ribavirin 10-15mg per kg every time
Intervention: TCM and Western Medicine (Drug)
Outcomes
Primary Outcomes
Mortality
Time Frame: Anytime of the clinical trail from 2011.1.1 to 2015.12.30
Secondary Outcomes
- Safety outcome(From 2012.1 to 2015.12)
Investigators
Xinghua Tan
Director of Department of infection area
Guangzhou 8th People's Hospital