ACTRN12619000693123招募中未知
Does guideline-based dosing of beta lactam antibiotics and vancomycin achieve the target drug concentrations more than therapeutic drug monitoring-based dosing in critically ill patients? (GUIDE TRIAL)
Paul Williams0 个研究点目标入组 150 人开始时间: 2019年5月8日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Written informed consent obtained from the patient or their legally authorised representative
- •Aged 18 years or over
- •Patient is an inpatient of the ICU
- •Patient prescribed at least one of the study antibiotics to treat an infection
- •Prescribed flucloxacillin, cefepime, piperacillin/tazobactam, meropenem or vancomycin
- •via a continuous or intermittent dosing regimen
- •Suitable intravenous/intra-arterial access to facilitate sample collection
排除标准
- •Consent not obtained
- •Aged less than 18 years
- •Not being administered any of the study antibiotics
- •Study antibiotics have been administered for greater than 72 hours prior to enrolment
- •Limited or no intravenous/intra-arterial access.
- •Known to be pregnant
- •Prophylactic antibiotics
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