A prospective randomised controlled trial on the postoperative analgesic efficacy of ultrasound guided external oblique intercostal plane block versus port site infiltration in patients undergoing laparoscopic cholecystectomy

This study will be conducted as a prospective, parallel-arm, randomized controlled trial done for a period of two years , comparing the postoperative analgesic efficacy of ultrasound-guided external oblique intercostal plane (EOI) block with port-site infiltration in patients undergoing laparoscopic cholecystectomy. Eligible patients will be randomly assigned to either Group A (EOI block) or Group B (port-site infiltration) using a computer-generated random number sequence. Allocation concealment will be ensured through sealed opaque envelopes. The investigator performing postoperative assessments will be blinded to group allocation. The final sample size will be 20 participants per group (total 40).Primary Outcome measures Pain scores at 1, 2, 6, 12, and 24 hours using the NRS. Secondary Outcomes are time to first intravenous rescue analgesic,total  dose of IV analgesic required in 24 hours,frequency  of IV analgesia administration, incidence of postoperative nausea and vomiting (PONV) , patient satisfaction score (Likert scale).