Perioperative concentrations of reactive oxygen species in the cerebrospinal fluid of neurosurgically treated patients
Recruiting
- Conditions
- redox processes
- Registration Number
- DRKS00031776
- Lead Sponsor
- niversitätsklinikum Freiburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
patients receiving a CSF puncture
Exclusion Criteria
a) All patients who are younger than 18 years old
b) Patients who do not agree to the research project
c) CSF samples from which, directly or indirectly, there is a diagnostic or therapeutic consequence for the patient in question
d) CSF samples that would not be immediately discarded, destroyed or disposed of without the present research project
e) Contain an amount of less than 5 milliliters.
f) Are visibly contaminated by blood or foreign substances.
g) Are cloudy or have precipitates.
h) show signs of an inflammatory change.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Determination and differentiation of the concentration of reactive oxygen species (including hydrogen peroxide (H2O2)) in the cerebrospinal fluid
- Secondary Outcome Measures
Name Time Method Verification of the suitability of electron spin resonance and the Amplex™ Red hydrogen peroxide/peroxidase assay for the determination of reactive oxygen species (including hydrogen peroxide (H2O2)) from cerebrospinal fluid