Obstetric Outcomes After Double Embryo Transfer in Intracytoplasmic Sperm Injection
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 927
- 试验地点
- 1
- 主要终点
- Live birth
研究概览
简要总结
Aim ; to compare obstetric outcomes in relation to number of embryo transfer in ICSI
详细描述
Assisted reproductive technology with intracytoplasmic sperm injection (ICSI) and IVF is becoming an international direction for couples struggling with infertility. The increasing popularity and frequency of these techniques and the data generated from it has given us a better overview of the efficacy, consequences and costs of these techniques.
The aim of assisted reproductive technology (ART) is to achieve pregnancy while decreasing the risk of multiple gestations. When compared with elective single embryo transfer (SET), double embryo transfer (DET) demonstrates a superior pregnancy and live birth rate with a significantly higher risk of multiple gestations. The high frequency of multiple births is the main factor which leads to adverse outcome in IVF/intracytoplasmic sperm injection (ICSI) treatment. Transfer of two embryos does not diminish the chance of a birth when compared with three embryo transfer. How would be the obstetric outcome in pregnancies resulting from DET in IVF/ICSI cycles.
Despite achieving a higher pregnancy rates, DET in ART leads to an increase in multiple gestation pregnancies, which are associated with increased both maternal and neonatal morbidity and mortality.
Twin pregnancies have a higher incidence of preterm cesarean sections , admissions to the neonatal intensive care unit (NICU), and other maternal complications, when compared with singleton pregnancies. Twin pregnancies have a higher incidence of preterm cesarean sections , admissions to the neonatal intensive care unit (NICU), and other maternal complications, when compared with singleton pregnancies.
Most patients prefer to have two embryos transferred, due to financial considerations being the main reason.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •all patients subjected with ICSI pregnancy
排除标准
- •incomplete data
结局指标
主要结局
Live birth
时间窗: 1 year
Comparison
次要结局
- Rate of admission to NICU(1 year)
- Rate of Clinical pregnancy(1 year)
- Rate of chemical pregnancy(1 year)
- Rate of neonatal morbidities and mortalities in single embryo transfer versus double embryo transfer(1 year)
- Rate of miscarriage(1 year)
- Rate of multiple pregnancies(1 year)
- Rate of PPROM(1 year)
- Rate of preterm(1 year)
研究者
Ahmed Shehata Mohamed Ismail
Faculty of medicine, Assiut University, 71515 Assiut, Egypt
Assiut University
