Treatment of Neck Metastases from Thyroid Cancer by Ultrasound Guided Ablatio
- Conditions
- Thyroid Gland NeoplasmC04.588.322.894
- Registration Number
- RBR-4wzd8p
- Lead Sponsor
- Instituto do Câncer do Estado de São Paulo - ICESP
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
18 years of age or older; Patients with fine needle aspiration biopsy (FNAb)-proven metastatic cervical lymph nodes at levels I, II, III, IV, V, VI or VII from thyroid carcinoma (well differentiated, papillary - PTC or medullary) who underwent total thyroidectomy and subsequent radioiodine therapy, in case of PTC; Patients considered high surgical risk candidate or patients who are informed about the ablation therapy and prefers it instead surgery; Patients with metastatic cervical lymph nodes over 0.8 cm diameter and under 4.0 cm diameter; no more than 6 metachronous cervical nodal metastases; Cervical recurrences in previously lateral neck dissection patients for well differentiated papillary or medullary thyroid carcinoma over 0.8 cm diameter.
Age under 18 years; Uncorrectable coagulopathy; Inconclusive or benign cytologic specimens; Pregnancy or breast-feeding; Anaplastic or poor-differentiated thyroid carcinoma; Partial thyroidectomy; Cervical tumors not considered to surgery (invading vessels, nerves, larynx or trachea); Serious medical illness, including any of the following: uncontrolled angina, myocardial infarction, cerebrovascular event within 6 months prior to the baseline visit, uncontrolled congestive heart failure; Participation in other studies that could affect the primary endpoint
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Feasibility and safety evaluation of thermal ablation of thyroid carcinoma cervical lymph node metastases
- Secondary Outcome Measures
Name Time Method