Edessy ICSI Outcome Embryo Score (EIOS) Efficacy

Phase 1

Completed

Conditions: Infertility

Interventions: Other: Edessy ICSI Outcome Embryo Score

Registration Number: NCT02082288

Lead Sponsor: Al-Azhar University

Brief Summary: Purpose of this study is to detect outcome of intracytoplasmic sperm injection (ICSI) according to EIOS

Detailed Description: A total of 243 infertile couples underwent long GnRH agonist protocol in the ART unit, International Islamic Center for Population Studies and Research (IICPSR), Al-Azhar University.

Embryos which reached the two cell stage at 25-27 hr were classified as EC, and the remaining as Non Early Cleavage embryos (NEC). Embryos were assessed again at 64-68 hours post-ICSI for day three embryo morphology score (Loi et al.,2008). The best two or three embryos, according to day 3 embryo morphology were transferred. Each patient was given a score according to EIOS (female age, number of retrieved oocytes, number of EC embryos, number of good quality embryos and number of embryos transferred).

Recruitment & Eligibility

Status: COMPLETED

Sex: Female

Target Recruitment: 243

Inclusion Criteria

Age ≤ 40 years old. BMI >25 - 30 kg/m2. Have two ovaries. Regular cycles. 1st ICSI cycle. Long midluteal GnRH protocol

Exclusion Criteria

uterine factor as a cause of female factor infertility. pelvic masses or diseases (e.g: endometriosis, fibroids, hydro- salpnix, ...). history of medical disorders (e.g: hypertension, D.M, thyroid dysfunction, liver diseases, renal diseases,...).

azoospermia as a cause of male factor infertility.

Study & Design

Study Type: INTERVENTIONAL

Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Edessy ICSI Outcome Embryo Score	Edessy ICSI Outcome Embryo Score	ICSI

Primary Outcome Measures

Name	Time	Method
Clinical Pregnancy	6 weeks	A clinical pregnancy will be determined by identifying the presence of a gestational sac at six weeks gestation on transvaginal ultrasonography.

Secondary Outcome Measures