Edessy ICSI Outcome Embryo Score (EIOS) Efficacy
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 243
- 试验地点
- 1
- 主要终点
- Clinical Pregnancy
研究概览
简要总结
Purpose of this study is to detect outcome of intracytoplasmic sperm injection (ICSI) according to EIOS
详细描述
A total of 243 infertile couples underwent long GnRH agonist protocol in the ART unit, International Islamic Center for Population Studies and Research (IICPSR), Al-Azhar University.
Embryos which reached the two cell stage at 25-27 hr were classified as EC, and the remaining as Non Early Cleavage embryos (NEC). Embryos were assessed again at 64-68 hours post-ICSI for day three embryo morphology score (Loi et al.,2008). The best two or three embryos, according to day 3 embryo morphology were transferred. Each patient was given a score according to EIOS (female age, number of retrieved oocytes, number of EC embryos, number of good quality embryos and number of embryos transferred).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age ≤ 40 years old. BMI >25 - 30 kg/m
- •Have two ovaries. Regular cycles. 1st ICSI cycle. Long midluteal GnRH protocol
排除标准
- •uterine factor as a cause of female factor infertility. pelvic masses or diseases (e.g: endometriosis, fibroids, hydro- salpnix, ...). history of medical disorders (e.g: hypertension, D.M, thyroid dysfunction, liver diseases, renal diseases,...).
- •azoospermia as a cause of male factor infertility.
结局指标
主要结局
Clinical Pregnancy
时间窗: 6 weeks
A clinical pregnancy will be determined by identifying the presence of a gestational sac at six weeks gestation on transvaginal ultrasonography.
次要结局
未报告次要终点
研究者
Edessy Mahmoud
al-azhar unversity (assuit), faculty of medicine, obstetrics and gynecology department
Al-Azhar University