The effects of palmitate and chicoric acid on diabetes
Not Applicable
Recruiting
- Conditions
- Diabetes.Non-insulin-dependent diabetes mellitus
- Registration Number
- IRCT2017071535085N1
- Lead Sponsor
- Hamadan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
FBS greater than 126 mg/dL; 2 hours blood glucose greater than 200 mg/dl; HbA1C greater than 6.5%; The control group should have a fasting blood glucose less than 100 mg/dl.
Exclusion criteria:
Use of medications such as antihypertensive drugs (such as beta-blockers), anti-diabetic drugs, estrogen supplements, thyroxine, diuretics and hypolipemic drugs; Other chronic and acute inflammatory diseases such as chronic kidney disease, cardiovascular disease, hypertension and ...; Infectious diseases, cancer, allergies; Other Endocrine Disorders (Except Type 2 Diabetes); Pregnancy; Smoking
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method SIRT1. Timepoint: One day after the intervention, Two day after the intervention. Method of measurement: Gene expression of SIRT1 using Ct of gene.;IL-6. Timepoint: One day after the intervention, Two day after the intervention. Method of measurement: Gene expression of IL-6 using Ct of gene.;P-AMPK. Timepoint: One day after the intervention, Two day after the intervention. Method of measurement: concentration of p-AMPK using western blotting.
- Secondary Outcome Measures
Name Time Method