CTRI/2025/08/092627尚未招募3 期
Comparative Evaluation of the Depth of Penetration and Postoperative Pain Associated with the Use of Standard Irrigation Protocol and Continuous Chelation Using HEBP with and Without the Use of Ultrasonic Activation in the Endodontic Treatment of Adult Permanent Teeth with Necrotic Pulp A Randomized Controlled Trial
Dr. Krishma Mehra1 个研究点 分布在 1 个国家目标入组 75 人开始时间: 2025年9月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- Outcome will be assessed on clinical evaluation and radiographic assessment
研究概览
简要总结
The study compares traditional NaOCl/EDTA sequential irrigation with continuous chelation using HEBP and NaOCl, with or without ultrasonic activation, in adult teeth with necrotic pulp. Mechanical instrumentation alone may leave 35% of the canal untouched, so irrigants are vital. Continuous chelation simplifies procedures and maintains NaOCl’s antibacterial potency while reducing structural damage. The goal is to assess which method offers deeper irrigant penetration and minimizes postoperative pain.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult permanent asymptomatic teeth with necrotic pulp requiring non surgical endodontic treatment Teeth whose non-vitality was confirmed by an electric pulp tester (EPT) and thermal sensitivity testing Feasibility of isolating the tooth with a rubber dam Vertucci Type I and Type IV root canal anatomy Participants with the ability to understand the consent forms and the pain record scales.
排除标准
- •Nonvital tooth with periapical lesion Patients with spontaneous preoperative pain Patients who had taken Nonsteroidal anti-inflammatory drugs or any other analgesic for pain within the last 4–8 h Teeth with calcified root canals and complex root canal anatomy.
- •Teeth with open apices, and resorbed apex Periodontally compromised teeth The patient who is not willing to give consent for the study Patients with known allergies to the materials used in the study.
结局指标
主要结局
Outcome will be assessed on clinical evaluation and radiographic assessment
时间窗: 6 hours and 48 hours
次要结局
- Outcome will be assessed on clinical evaluation and radiographic assessment(During treatment)
研究者
Dr Krishma Mehra
Himachal Dental College and Hospital
研究点 (1)
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