Skip to main content
Clinical Trials/NCT07618117
NCT07618117Not yet recruitingNot Applicable

Mitigating Cardiometabolic Risk by Improving Sleep Health and Circadian Timing in Adolescents With Overweight/Obesity

University of Colorado, Denver0 sites60 target enrollmentStarted: August 25, 2026Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
60

Study Overview

Brief Summary

Many teenagers get too little and late timed sleep. High body weight and diabetes are increasing in teenagers as well. This study plans to learn more about whether improving sleep habits can help improve how the body regulates blood sugar and energy use in teenagers who have higher body weight. To answer this question, the investigators plan to enroll teenagers who get <7 hours of sleep on school nights and measure changes in blood sugars and energy use after two weeks of typical sleep (sleeping on their normal school schedule) and two weeks of a sleep intervention that includes spending longer time in bed at night, melatonin, and morning light.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
14 Years to 19 Years (Child, Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • High school students between 14-19 years
  • Overweight/obesity (BMI >85% for age and sex)
  • Have habitually insufficient sleep, defined as ≤ 7 hours per night on school days
  • Habitually inactive (≤ 3 h of physical activity reported per week)
  • Tanner stage 4 or 5, based on breast development for girls and testicular size for boys.

Exclusion Criteria

  • Reported diagnosis of sleep disorder (e.g., insomnia, obstructive sleep apnea)
  • Medical comorbidities that impact sleep or insulin sensitivity (e.g., diabetes [based on history or screening HbA1c])
  • Regular use of medications affecting sleep or insulin sensitivity (e.g., stimulants, sleep aids, systemic steroids, insulin sensitizers, GLP-1 agonists)
  • IQ<70 or severe mental illness that may impact sleep or study participation (e.g., schizophrenia), eating disorder, or active suicidal ideation
  • Schedules that would preclude participants from adhering to the sleep schedules (e.g., night-shift employment)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Similar Trials