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临床试验/NCT03976947
NCT03976947已完成不适用

Impact of Lung Recruitment Maneuvers on Driving Pressure in Cardiac Surgery (IMPREMO): Before - After Trial

University Hospital, Caen1 个研究点 分布在 1 个国家目标入组 217 人开始时间: 2017年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
217
试验地点
1
主要终点
Driving pressure variation due to lung recruitment maneuvers

研究概览

简要总结

In anesthesia the incidence of postoperative pulmonary complications is frequent, especially in cardiac surgery where the incidence can reach 10%. Respiratory morbidity in cardiac surgery is favored by multiple factors and is higher compared to anesthesia in "general" surgery. The prevention of these complications is a major challenge in the management of patients.

Influence of driving pressure level on respiratory morbidity was first demonstrated in management of acute respiratory distress syndrome (ARDS) in resuscitation.

More recently, this notion has been introduced in anesthesia, with a correlation between increase driving pressure level and increase of post-operative respiratory complications.

A method should reduce these levels of driving pressure: performing lung recruitment maneuvers. This technique has been successfully tested in abdominal surgery in particular in a study published by Futier et al.. They systematized and standardized lung recruitment maneuvers and showed a decrease of postoperative pulmonary complications in abdominal surgery.

Thus, the realization of lung recruitment maneuvers, already used at the discretion of the practitioner, is now recommended by several teams of experts. The investigators propose in this "before-after" trial to evaluate variation in driving pressure due to systematic use of lung recruitment maneuvers, observed in patients operated in elective or urgent surgery. The secondary objective is to evaluate their impact on postoperative pulmonary complications.

详细描述

This is a retrospective, before / after, monocentric trial.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients receiving elective or urgent cardiac surgery with cardiopulmonary bypass

排除标准

  • Emergency or salvage surgery
  • Patient under guardianship
  • Pregnancy

结局指标

主要结局

Driving pressure variation due to lung recruitment maneuvers

时间窗: 1 day

cmH2O

次要结局

  • Incidence of postoperative pulmonary complications(baseline)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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