Efficacy of human atrial natriuretic peptide for the patients with severe sepsis; Impact on prevention against acute kidney injury
Not Applicable
- Conditions
- Severe sepsis
- Registration Number
- JPRN-UMIN000003821
- Lead Sponsor
- Tosei General Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
Patients are excluded (a)if they have already introduced maintenance HD before admission, (b)have got abdominal surgery for perforation of digestive tract, (c)have fallen in sepsis for more than 48 hours before the start of antibiotic therapy, (d)can't get out of septic shock within 72 hours after the start of antibiotic therapy, (e)have severe chronic heart failure as NYHA III or IV, (f)known pregnancy, (g)expected stay in the intensive care unit of less than 3 days, or (h)poor chance of survival.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 30-day mortality
- Secondary Outcome Measures
Name Time Method Renal function Introduction of maintenance haemodialysis (HD) Ventilator free days 90-day mortality