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ew therapeutic approaches for anaplastic thyroid cancer: assessment of the benefit-risk profile of the combination valproic acid-paclitaxel. - ND

Conditions
Patients with undifferentiated thyroid cancer
MedDRA version: 9.1Level: LLTClassification code 10002240Term: Anaplastic thyroid cancer
Registration Number
EUCTR2008-005221-11-IT
Lead Sponsor
AZIENDA SANITARIA OSPEDALIERA S. GIOVANNI BATTISTA DI TORINO
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1.Patients with undifferentaited thyroid cancer treated with paclitaxel
2.Age> 18 years
3.Performance status ≤ 3 (ECOG).
4.Availability to give a written informed consent
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

1.Hepatic (bilirubin > 2mg/dl; ALT > 3 times the upper limit of normality) and/or renal (creatinine > 2mg/dl) failure
2.Thrombocytopenia and/or thrombocytopathy
3.Treatment with aspirin or antiplatelet agents
4.Treatment with antipsychotic drugs
5.Impossibility to get an informed consent due to impaired consciousness
6.Pregnant or breastfeeding women
7.Fertile women not taking contraceptive pills

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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