Beneficial Effects of Herbal Tea on Lipid Profile, Insulin Resistance, CRP, CBC, Liver, and Kidney Function Tests, and Anthropometric Indices in Jordanian Adults
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Questionnaire
研究概览
简要总结
investigate beneficial effect of an herbal tea prepared from carob pulp and pods (Ceratonia siliqua), anise seed (Pimpinella Anisum L), wild thyme, green tea and eucalyptus leaves with Manuka honey (natural sweetener) on lipid profile and insulin resistance, CRP (C-reactive protein), CBC (complete blood count), liver function test, kidney function tests, inflammation and anthropometric indices in adults living in Amman Jordan
详细描述
This study will be carried out to examine the effect of herbal tea in recruited subjects in an intervention single-group pretest-posttest study for a period of 7 weeks. Subjects will consume twice a day for a period of 7 weeks an herbal tea of (carob, anise, wild thyme, and eucalyptus leaves) before eating. The total sample (n=30) adults aged (19-57 years) , body mass index BMI range (19-35 kg/m2)
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 57 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •adults aged 19-57 years
- •male to female ratio (1:1 ratio)
- •BMI 19-35 kg/m2
- •Currently living in Amman
- •without significant apparent diseases
- •Able to drink the tested herbal tea twice a day
排除标准
- •Have chronic diseases such as diabetes, hypertension, cardiovascular or endocrine diseases or disabilities
- •Using medical drugs and/or supplements
- •Below 19 or above 57 years.
- •participation in clinical trials within the last 2 months
- •use of lipid-lowering drugs, or diabetic medication.
- •Lactating and pregnant women will be also excluded.
研究组 & 干预措施
adults aged 19-57
adults aged 19-57 years old living in Amman Jordan, body mass index between 19-57
干预措施: herbal tea intervention (Other)
结局指标
主要结局
Questionnaire
时间窗: 1-2 weeks
basic demographic information
Homocysteine serum level
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by umol/L normal range \< 12 umol/L
Fasting blood sugar
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by mg/dL normal range 70-99 mg/dL
Glycosylated Haemoglobin (HBA1C) blood
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by percentage normal range 4.8-5.8%
Cholesterol serum
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by mg/dL normal range \<200 mg/dL
Triglyceride serum
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by mg/dL normal range \<150 mg/dL
HDL cholesterol(High density lipoprotein) serum
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by mg/dL normal range \>60mg/dL
Cholesterol/HDL Ratio
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates normal range \<4.0
Protein serum
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by g/dL normal range 6.0-8.0g/dL
C-Reactive Protein high sensitivity serum
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by mg/dL , low risk of CVD \<1.0 mg/dL
Insulin serum
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by uU/ml normal range 2.6-24.9
Cortisol Total (AM) serum
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by ug/dL normal range 6.02-18.4
Tumor Necrosis Factor
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by pg/mL normal range upto 8.1
8-OH-2 Desoxyyguanosine urine
时间窗: 7 weeks pre and post intervention
Urine sample measured by micromol/mol normal range 0.1-2.4
interleukin 1 Beta
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by pg/ml normal range upto 5 pg/ml
weight
时间窗: 7 weeks pre and post intervention
measured on inbody 770 measured by kg
Height
时间窗: pre intervention
measured by cm
LDL Cholesterol (low density lipoprotein) serum
时间窗: 7 weeks pre and post intervention
venous blood sample for 30 candidates measured by mg/dL normal range \<100mg/dL
次要结局
- gastrointestinal symptoms questionnaire(7 weeks pre and post intervention)
- Creatinine serum(7 weeks pre and post intervention)
- Alanine Aminotransferase (ALT/GPT) serum(7 weeks pre and post intervention)
- Aspartate Aminotransferase (AST/GOT) serum(7 weeks pre and post intervention)
- Gamma-Glutamyl Transferase (GGT) serum(7 weeks pre and post intervention)
- Alkaline phosphatase serum(7 weeks pre and post intervention)
- Creatine phospho Kinase (CPK)(7 weeks pre and post intervention)
- Microalbuminuria spot urine(7 weeks pre and post intervention)
- Creatinine spot urine(7 weeks pre and post intervention)
- Microalbuminuria-Creatinine spot urine(7 weeks pre and post intervention)
- Haemoglobin(7 weeks pre and post intervention)
- haematocrit(7 weeks pre and post intervention)
- Erythrocytes(7 weeks pre and post intervention)
- MCV(7 weeks pre and post intervention)
- MCH(7 weeks pre and post intervention)
- MCHC(7 weeks pre and post intervention)
- RDW- cv(7 weeks pre and post intervention)
- Leukocytes(7 weeks pre and post intervention)
- platelets(7 weeks pre and post intervention)
- Skeletal muscle mass(7 weeks pre and post intervention)
- Body fat mass(7 weeks pre and post intervention)
- Percent body fat mass(7 weeks pre and post intervention)
- free fat muscle(7 weeks pre and post intervention)
- Visceral fat are(7 weeks pre and post intervention)
- total body water(7 weeks pre and post intervention)
- Body mass index(7 weeks pre and post intervention)
- Basal metabolic rate(7 weeks pre and post intervention)
- waist circumference(7 weeks pre and post intervention)
- Hip circumference(7 weeks pre and post intervention)
- Waist/hip ratio(7 weeks pre and post intervention)
- Waist/height ratio(7 weeks pre and post intervention)
研究者
Dr.Ruba Musharbash
Principal investigator
Ruba Musharbash Nutrition Consultancy Center