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a explorative study of nutritional state and the effect of diet intervention on body composition, muscle strength, activity, pulmonary function and quality of life in adults with mitochondrial disease caused by the m.3243A.G mutation.

Completed
Conditions
m. 3243A.G mutation
Mitochondrial disease
OXPHOS deffect
MELAS
MIDD
10021605
10027424
Registration Number
NL-OMON39342
Lead Sponsor
niversitair Medisch Centrum Sint Radboud
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
50
Inclusion Criteria

Proven mitochondrial m. 3243A>G mutation
age > 18 years
No medical contra indication for reseaving Nutritional assesment in sober state.
informed consent

Exclusion Criteria

sober state is contra indicated for medical reasons, for exemple to high risk for hypoglycemia
pacemaker, any implantations made from metal
claustrophobia
no informed consent

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>nutritional status.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>activity, lung function, hand grip strength, body composition, food intake,<br /><br>fatigue and quality of life.</p><br>
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