Correlation of ELWI, tissue edema and blood flow in COVID-19 patients treated with extracorporeal membrane oxygenatio

• Conditions: COVID-19 lung failure; J80.03

• Registration Number: DRKS00026246
• Lead Sponsor: Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsmedizin Mannheim

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-09-14
• Study Completion: 2022-03-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 128

Inclusion Criteria

All patients who were treated in our ICU for respiratory failure with or without SARS-CoV-2 infection and extracorporeal membrane oxygenation therapy between the years 2016 and today.

Exclusion Criteria

All patients with respiratory failure who did not receive extracorporeal membrane oxygenation therapy.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Is there a linear correlation between the EVLWI measured via transpulmonal thermodilution (PICCO) and the actual lung edema measured via CT-scans in patients suffering from respiratory failure due to COVID-19 and receiving extracorporeal membrane oxygenation therapy (ECMO)?

Secondary Outcome Measures

Name	Time	Method
How does the extracorporeal membrane oxygenation blood flow correlate with the extravascular lung water index (EVLWI) and the pulmonary oedema determined by computed tomography?