Cerebral near-infrared spectroscopy monitoring in infants during the peri-operative period: a prospective observational cohort study
Not Applicable
Completed
- Conditions
- Cerebral deoxygenationNeurodevelopmental outcomeAnaesthesiology - Anaesthetics
- Registration Number
- ACTRN12614000292673
- Lead Sponsor
- The Royal Children's Hospital Melbourne
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 240
Inclusion Criteria
Infants aged less than 6 months of age (corrected) scheduled for anaesthesia that is expected to last longer than 30 minutes duration.
Exclusion Criteria
1. Children where application of the NIRS would be impractical: for example surgery on the head or neck of the child.
2. Children scheduled for cardiac surgery
3. Children with known major cardiovascular shunting
4. Children with known neurological abnormalities
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cerebral oxygenation levels[Perioperative period (pre, intra and post-operatively).<br>We will record the NIRS for a short period pre-operatively (5-10 minutes) while the participant is awake and resting quietly. We will record NIRS post-operatively until the participant fully awakes (or up to a maximum of 30 minutes).]
- Secondary Outcome Measures
Name Time Method Blood pressure readings will be recorded using a manual sphygomanometer pre and post-operatively. We will use an automatic sphygomanometer to record blood pressure intraoperatively. Where possible, we will also record intra-arterial blood pressure to allow high frequency analysis.[Several blood pressure readings will be recorded over a 5-10 minute period pre-operatively when the child is awake and resting. Blood pressure readings will be recorded every 2.5 minutes pre-operatively. We will also collect blood pressure readings post-operatively until the child fully awakes (or up to a maximum of 30 minutes).]