Study on effect of how Ozonated Olive Oil Affects Wound Healing and Bone Growth Around Dental Implants"

Not yet recruiting

• Conditions: Other specified disorders of gingiva and edentulous alveolar ridge, (2) ICD-10 Condition: K068||Other specified disorders of gingiva and edentulous alveolar ridge,

• Registration Number: CTRI/2025/04/084932
• Lead Sponsor: Sandra Haritha

Brief Summary

This study is an randomiz ed clinical trial comparing the effects of Ozonated olive oil on hard tissue and soft tissue changes around non submerged dental implants After patient selection based on eligibility criteria ,Phase1 therphy oral prophylaxis and surgical stunt fabrication will be done and patient will be recalled after 1week.The procedure will be performed under local anesthesia using 2%lignocaine containing adrenaline in 1:80,000 ratio .A mid crestal incision will be given and osteotomy site will be prepared.   In Group1 implants without Ozonated olive oil will be placed .In Group 2 Implants coated with Ozonated olive oil will be placed.After placement stability will be checked with resonance frequency analysis at baseline .Healing abutment will be placed and flaps will be approximated and sutured. Patient will be recalled after 1st week,2nd week for evaluating wound healing 3months and 6months for crestal bone level and 3months for implant stability.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-01-06
• Last Update Posted: 2025-09-04

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

• 1.Individuals with an age group of 20-60 years of either gender 2.Presence of adequate horizontal(4-5mm) and vertical (12mm) dimensions of the alveolar bone based on CBCT.
• 3.Presence of adequate keratinized mucosa (minimum 1 mm) in the edentulous site.
• 4.Apparently healthy individuals.
• 5.Individuals with bone density classified as D2 and D3 type of bone.

Exclusion Criteria

• 1.Any forms of tobacco users.
• 2.Pregnant and lactating women.
• 3.Subjects taking any medication which effect healing and bone metabolism.
• 4.Individuals with parafunctional habits.
• 5.History of radiotherapy to head and neck.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the wound healing around implants coated with ozonated olive oil.	1st week &2nd week after surgery

Secondary Outcome Measures

Name	Time	Method
To evaluate the crestal bone level around implants coated with ozonated olive oil.	Baseline ,3 months and 6 months
To evaluate Implant stability around implants coated with Ozonated olive oil	Baseline and 3months.

Trial Locations

Locations (1)

Sibar Institute of Dental Sciences; 🇮🇳 Guntur, ANDHRA PRADESH, India

Sibar Institute of Dental Sciences

🇮🇳Guntur, ANDHRA PRADESH, India

Sandra Haritha

Principal investigator

7989752309

harithasandra951@gmail.com