Effects of Diagonal Proprioceptive Neuromuscular Facilitation Patterns on Pain and Functional Outcomes in Patients With Knee Osteoarthritis
概览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- Change in pain intensity will be assessed with Visual Analogue Scale
概览
简要总结
A randomized controlled trial will be conducted at the Department of Physiotherapy, Dr. Ziauddin Hospital and Al-Rayaz Hospital, Karachi, Pakistan. A total of 150 patients diagnosed with knee osteoarthritis, aged between 40-60 years, will be recruited through a non-probability purposive sampling technique. Written informed consent will be obtained from all eligible participants prior to enrollment. The participants will be randomly allocated by the help of computer generated randomization sheet, into two groups i.e. experimental and the control group, with 75 participants in each group. Group A (experimental group) will receive diagonal proprioceptive neuromuscular facilitation (PNF) pattern exercises, while Group B (control group) will receive conventional strength training exercises. Heat therapy will be administered to both groups. All participants will be assessed using a standardized assessment form. Outcome measures will include pain intensity, knee range of motion, functional disability, hamstring flexibility, dynamic balance, and fatigue level. A single blinded assessor will assess all participants at baseline and at post intervention. Treatment sessions will be given thrice a week on alternate days for 6 weeks.
详细描述
The Statistical Package for the Social Sciences (SPSS) version 23 will be used for data analysis. Mean and standard deviation will be calculated for quantitative variables such as age. Qualitative variables will be presented as frequencies and percentages. Outcome measures (decrease pain intensity, improve functional disability, increase knee range of motion, improve hamstring flexibility, dynamic balance, and fatigue level) recorded at baseline and after 18th session of intervention will be compared and analyzed. Repeated measures ANOVA will be applied for statistical analysis. A p-value of less than 0.05 will be considered as the level of statistical significance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Data analyst will also be blinded.
入排标准
- 年龄范围
- 40 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Both male and females with an age range between 40-60 years.
- •Patients diagnosed with unilateral or bilateral Knee OA.
- •Grade-II or grade-III on kellgren and Lawrence classification.
- •Patients having pain intensity more than 3.4 cm on VAS as minimum cut off value.
- •Duration of knee OA more than 3 months (chronic).
排除标准
- •Patients with any neurological disorder.
- •History of lower limb arthroplasty or any other knee surgery.
- •Septic knee arthritis.
- •Inflammatory rheumatic disease such as rheumatoid arthritis and gout.
- •Cancer or any other malignancy such as bone tumor.
- •Knee deformities such as contracture, genu valgum and genu varum.
- •History of ligamentous injury and meniscal tear.
研究组 & 干预措施
Diagonal Proprioceptive Neuromuscular Facilitation (PNF) Pattern Exercises + Heat Therapy.
This arm will receive PNF pattern exercises using Diagonal 1 and Diagonal 2 Lower Limb Patterns of PNF and the heat therapy
干预措施: Diagonal Proprioceptive Neuromuscular Facilitation (PNF) Pattern Exercises (Other)
Diagonal Proprioceptive Neuromuscular Facilitation (PNF) Pattern Exercises + Heat Therapy.
This arm will receive PNF pattern exercises using Diagonal 1 and Diagonal 2 Lower Limb Patterns of PNF and the heat therapy
干预措施: Heat Therapy (Other)
Conventional Strength Training Exercises + Heat Therapy
This arm will receive evidence based treatment of Quadripceps and Hip Abductor Strengthening exercises and the heat therapy.
干预措施: Conventional Strength Training Exercises (Other)
Conventional Strength Training Exercises + Heat Therapy
This arm will receive evidence based treatment of Quadripceps and Hip Abductor Strengthening exercises and the heat therapy.
干预措施: Heat Therapy (Other)
结局指标
主要结局
Change in pain intensity will be assessed with Visual Analogue Scale
时间窗: Baseline and after 6 weeks of intervention
The Visual Analogue Scale is a unidimensional measure of pain intensity, used to record patients' pain progression, or assess pain severity in different conditions. It is 0 to 10 cm scale. Patients rate their pain on the scale. Higher the score in centimeter, severe will be the pain experienced.
Change in range of motion will be assessed with Universal Goniometer
时间窗: Baseline and after 6 weeks of intervention.
The universal goniometer is an instrument for the precise measurement of range of movement angles in degree, especially one used to measure the angles before and after range of motion. Increase in the degree of angle suggests increase in range of movement.
次要结局
- Change in functional disability will be assessed with Knee Injury and Osteoarthritis Outcome Score (KOOS)(Baseline and after 6 weeks of intervention.)
- Change in hamstring flexibility will be assessed with Active Knee Extension test.(Baseline and after 6 weeks of intervention.)
- Change in dynamic balance will be assessed with Four Step Square Test (FSST)(Baseline and after 6 weeks of intervention.)
- Change in fatigue level will be assessed with Multidimensional Fatigue Inventory questionnaire.(Baseline and after 6 weeks of intervention.)
研究者
Rabia Hassan
Principal Investigator
University of Karachi