Safety and Efficacy of Different Onset Times of Treatment With Pulsed Dye Laser on Improvement of Surgical Scars

Not Applicable

Terminated

• Conditions: Scar
• Interventions: Procedure: pulsed dye laser therapy

• Registration Number: NCT00506363
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

The appearance of skin after surgery plays an important role in patient's self confidence and life style. In fact, Keloids and hypertrophic scars are abnormal wound responses appearing in predisposed individuals after surgery. Among different kind of lasers, used to improve the appearance of hypertrophic scars and keloids, pulsed dye laser is now being used successfully in treatment of scars. Pulsed dye laser is effective in improving the color, height, texture, and elasticity of scars. Also, treatment with this technique is noninvasive, minimally uncomfortable, and requires no anesthesia. This study will assess the efficacy and safety of different onset times of treatment with pulsed dye laser on improvement of surgical scars.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2007-07-23
• Study First Submitted QC: 2007-07-23
• Study First Posted: 2007-07-25
• Study Start: 2008-01
• Primary Completion: 2008-12
• Study Completion: 2009-01
• Status Verified: 2009-10
• Last Update Submitted: 2009-10-04
• Last Update Posted: 2009-10-06

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Surgical scar with minimum length of 6 cm

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Exclusion Criteria

• History of light sensitivity or photodermatoses
• History of adverse reactions to laser treatment

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
A	pulsed dye laser therapy	pulsed dye laser and dynamic cooling device on the day of suture removal
B	pulsed dye laser therapy	pulsed dye laser and dynamic cooling device 2 months after suture removal
C	pulsed dye laser therapy	dynamic cooling device

Primary Outcome Measures

Name	Time	Method
pigmentation, pliability, width and height of surgical scars	baseline, middle of the study, 1 and 3 months after the last treatment session

Secondary Outcome Measures

Name	Time	Method
1- Clinical appearance of scar 2- Patient's satisfaction (scar erythema, scar thickness and scar induration) - Adverse events	1 and 3 months after the last treatment session

Trial Locations

Locations (1)

Center for research and training in skin diseases and leprosy; 🇮🇷 Tehran, Iran, Islamic Republic of