Laser Therapy Effect on Oral Mucositis in Childhood Acute Lymphoblastic Leukemia Patients

Not Applicable

Recruiting

• Conditions: Oral Mucositis; Childhood Acute Lymphoblastic Leukemia

• Registration Number: NCT05452668
• Lead Sponsor: Children's Cancer Hospital Egypt 57357

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-7-5
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 51

Inclusion Criteria

Inclusion Criteria:<br><br> 1. Patients with Acute Lymphoblastic Leukemia in the induction therapy phase and have<br> oral mucositis grade 2 or more.<br><br> 2. Age: 3-14 years old of both genders.<br><br> 3. No previous treatment with laser.<br><br> 4. Ability to open mouth for more than 2 cm for the duration of laser application with<br> a level of cooperation (Frankl rating 3 or 4).<br><br> 5. Patients who still have 10 days in their induction therapy phase or can be followed<br> up for a mininum of 10 days after the development of oral mucositis<br><br>Exclusion Criteria:<br><br> 1. Patients receiving radiotherapy<br><br> 2. Received oral Cryotherapy or IV keratinocyte growth factor for oral mucositis<br><br> 3. Patients with unstable clinical condition (e.g. sepsis)<br><br> 4. Patients who will be withdrawn from participation according to their request or due<br> to loss in follow up

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain Assessment

Secondary Outcome Measures

Name	Time	Method
Oral Mucositis Severity: