Efficacy of Clozapine in Patients with Prolonged Methamphetamine Induced Psychotic Disorder: A Single-blind Comparison With Olanzapine

Phase 2

Conditions: Resistant Psychosis Induced by Methamphetamine.
This block contains a wide variety of disorders that differ in severity and clinical form but that are all related to the use of one or more drugs, which may or may not prescribe medicine. The third letter of the code identify the materials involved, and

Registration Number: IRCT2015112225191N1

Lead Sponsor: Iran University of Medical Sciences Vice chancellor for research

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 40

Inclusion Criteria

1- A psychotic disorder caused by prolonged use of methamphetamine (more than 1 month psychotic and at the same time cocaine has not); 2- obtaining the informed consent of the patient's guardian; 3- The absence of mental retardation (moderate or severe); 4- Non-organic neurological disease leading to clinical standpoint.
Exclusion criteria: 1- If the loss of white blood cells or neutrophils less than 3,000 is less than 1,500; 2- Unwillingness to continue to participate in the study.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The severity of Symptoms and Psychosis Protests. Timepoint: Baseline, the end of the fourth week and eighth week. Method of measurement: Based on the PANSS Scale.;Craving. Timepoint: At baseline, the end of the fourth week and eighth week. Method of measurement: Craving Beliefs Questionnaire (CBQ.

Secondary Outcome Measures

Name	Time	Method
Extrapyramidal Side Effects. Timepoint: Baseline, the end of the fourth week and eighth week. Method of measurement: Scale Extrapyramidal Side Effects ((ESRs.