NCT01796847已完成不适用
Influence of PTEN on Glycemic Variability and Clinical Outcome in the Critically Ill Patient.
University of Roma La Sapienza1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2012年12月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Length of ICU stay
研究概览
简要总结
Glycemic variability in critically ill patients is a recognized negative prognostic factor. The molecular mechanisms determining inter-patients variability in glucose metabolism during stress are not fully understood. The Phosphatase and Tensin homolog (PTEN) is known to influence glucose homeostasis by interfering in intracellular insulin signaling.
Aim of this study is to ascertain whether differential expression of PTEN in critically ill patients correlates with glycemic variability and clinical outcome.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •provision informed consent
排除标准
- •impaired fasting glucose levels
结局指标
主要结局
Length of ICU stay
时间窗: Day 1 up to day 28
次要结局
- Glycemic variability as expressed by standard deviation of the glycemia measurements(Day 1 up to day 28)
研究者
Alessandro Laviano
Associate Professor
University of Roma La Sapienza
研究点 (1)
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