The efficacy of flEcainide Compared To metOprolol in reducing Premature ventrIcular Complexes. An open label cross-over study in pediatric patients.
Not Applicable
- Conditions
- <p>frequent premature ventricular contractions frequent ventricular ectopic beats left ventricular dysfunction anti-arrhythmic drugs children frequente premature ventriculaire contracties frequente overslagen van de hartkamers linker kamer dysfunctie anti-aritmica kinderen</p>10007521
- Registration Number
- NL-OMON26689
- Lead Sponsor
- eiden University Medical CenterLeiden, the Netherlands
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 49
Inclusion Criteria
Age ¡Ý 1 year and < 18 years
- Structurally normal heart confirmed by echocardiography
Exclusion Criteria
- Age < 1 year, because of the significant chance of spontaneous resolution of PVCs
- Structural cardiac defects
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The acute effect of flecainide and metoprolol on the reduction of PVCs as measured on Holter registration.</p><br>
- Secondary Outcome Measures
Name Time Method <p>The function of the left and right ventricle as measured by echocardiography and cardiac magneticresonance imaging, and NT-pro-BNP levels in the blood.</p><br>