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临床试验/NCT02672618
NCT02672618Unknown不适用

Clinical Research to Explore Manifestations of Heart Failure Using Infrared Thermal Imaging Technology

Jing Huang4 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2015年11月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
200
试验地点
4
主要终点
Surface temperature (℃)of face and hand measured by Infrared (IR) camera

研究概览

简要总结

The purpose of this study is to explore manifestations of Heart Failure Using Infrared Thermal Imaging Technology.

详细描述

Temperature is a vital and useful indicator for various diseases.Infrared thermal imaging (IRTI) allows the temperature representation of the body surface by thermal distribution, where it depends on the complex relationships defining the heat exchange processes between skin tissue, inner tissue, local vasculature, and metabolic activity.

The decrease in cardiac output in heart failure activate a series of compensatory adaption that are intended to maintain cardiovascular homeostasis. One of most important adaptation is activation of sympathetic nervous system, which could cause peripheral cutaneous vasoconstriction and decrease the skim temperature. Hence, the skim temperature of heart failure would be lower than health people,but which could not discovery by eye. The investigators hypothesize that IRTI could evaluate heart failure by the imaging of temperature distribution in the face on early stages.The aim of this study is to determine the effectiveness of infrared thermal imaging in evaluating heart failure.

研究设计

研究类型
Observational
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Willing to participate in the trial and sign the informed consent form
  • •Aged: 18-85 years
  • •Was diagnosed as heart failure
  • •There is no trauma, infection, biopsy or puncture, hemorrhage and tumor in the corresponding detection site (face)
  • •There is no skin disease, heart, liver, kidney, gastrointestinal tract, hematopoietic system and mental, neurological has no serious diseases

排除标准

  • •Fever causes by any reasons, temperature higher than 37.4℃
  • •Renal failure
  • •Cerebrovascular diseases
  • •Moderate anemia or more
  • •Not willing to participate in clinical trials

结局指标

主要结局

Surface temperature (℃)of face and hand measured by Infrared (IR) camera

时间窗: up to 12 months

次要结局

  • LVEF(left ventricular ejection fraction)(up to 12 months)
  • proBNP(pro Brain Natriuretic Peptide)(up to 12 months)
  • Entropy of thermal image(up to 12 months)
  • catecholamine levels(up to 12 months)

研究者

发起方
Jing Huang
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Jing Huang

professor,vice director

The Second Affiliated Hospital of Chongqing Medical University

研究点 (4)

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