Clinical Research to Explore Manifestations of Heart Failure Using Infrared Thermal Imaging Technology
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 4
- 主要终点
- Surface temperature (℃)of face and hand measured by Infrared (IR) camera
研究概览
简要总结
The purpose of this study is to explore manifestations of Heart Failure Using Infrared Thermal Imaging Technology.
详细描述
Temperature is a vital and useful indicator for various diseases.Infrared thermal imaging (IRTI) allows the temperature representation of the body surface by thermal distribution, where it depends on the complex relationships defining the heat exchange processes between skin tissue, inner tissue, local vasculature, and metabolic activity.
The decrease in cardiac output in heart failure activate a series of compensatory adaption that are intended to maintain cardiovascular homeostasis. One of most important adaptation is activation of sympathetic nervous system, which could cause peripheral cutaneous vasoconstriction and decrease the skim temperature. Hence, the skim temperature of heart failure would be lower than health people,but which could not discovery by eye. The investigators hypothesize that IRTI could evaluate heart failure by the imaging of temperature distribution in the face on early stages.The aim of this study is to determine the effectiveness of infrared thermal imaging in evaluating heart failure.
研究设计
- 研究类型
- Observational
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 85 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Willing to participate in the trial and sign the informed consent form
- •Aged: 18-85 years
- •Was diagnosed as heart failure
- •There is no trauma, infection, biopsy or puncture, hemorrhage and tumor in the corresponding detection site (face)
- •There is no skin disease, heart, liver, kidney, gastrointestinal tract, hematopoietic system and mental, neurological has no serious diseases
排除标准
- •Fever causes by any reasons, temperature higher than 37.4℃
- •Renal failure
- •Cerebrovascular diseases
- •Moderate anemia or more
- •Not willing to participate in clinical trials
结局指标
主要结局
Surface temperature (℃)of face and hand measured by Infrared (IR) camera
时间窗: up to 12 months
次要结局
- LVEF(left ventricular ejection fraction)(up to 12 months)
- proBNP(pro Brain Natriuretic Peptide)(up to 12 months)
- Entropy of thermal image(up to 12 months)
- catecholamine levels(up to 12 months)
研究者
Jing Huang
professor,vice director
The Second Affiliated Hospital of Chongqing Medical University
