Anatomical Right Posterior Sectionectomy of the Liver by IOUS-Guided Finger Compression

• Conditions: Liver Malignancies; Colorectal Liver Metastases; Hepatocellular Carcinoma
• Interventions: Procedure: Anatomical right posterior sectionectomy of the liver by IOUS-guided finger compression.

• Registration Number: NCT00797251
• Lead Sponsor: University of Milan

Brief Summary

The use of intraoperative ultrasound (IOUS) allows us to perform new conservative hepatectomies. The investigators previously reported the systematic subsegmentectomy by IOUS-guided finger compression for segments 2-3, which is currently applied for patients with hepatocellular carcinoma (HCC)on cirrhosis. The investigators herein describe a novel technique, which consists in the systematic right posterior sectionectomy by IOUS-guided finger compression.

Detailed Description

A novel technique for the demarcation of the resection area by means of IOUS-guided finger compression to accomplish a right posterior sectionectomy is described. Dissection or encirclement of the sectional pedicles for resection area demarcation is thus avoided. Ten patients underwent this technique successfully without mortality or major morbidity. IOUS-guided finger compression of sectional portal pedicle feeding the right posterior section is a feasible, safe, and effective method.

Study Timeline

• Study Start: 2007-09
• Status Verified: 2008-11
• Study First Submitted: 2008-11-24
• Study First Submitted QC: 2008-11-24
• Last Update Submitted: 2008-11-24
• Study First Posted: 2008-11-25
• Last Update Posted: 2008-11-25
• Primary Completion: 2009-01
• Study Completion: 2009-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Patients with tumors at least at 1 cm distally to the bifurcation of the right portal vein (bifurcation of P5-8 and P6-7) eligible for right posterior sectionectomy, namely the anatomical removal of segment 6 and 7, were considered potential candidates to this procedure. Precisely, these criteria were adopted:

  • Patients with hepatocellular carcinoma (HCC) with infiltrative growing pattern in contact with P6-7;
  • Patients with any type of HCC in contact with P6-7 with distal bile duct dilation;
  • Patients with colorectal liver metastasis (CLM) in contact with P6-7.

Exclusion Criteria

• Exclusion criteria for carrying out the herein described procedure was considered the presence of tumoral thrombosis in P6-7.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Right posterior section group	Anatomical right posterior sectionectomy of the liver by IOUS-guided finger compression.	Patients with tumors in the right posterior section of the liver (segments 6-7)

Primary Outcome Measures

Name	Time	Method
The primary outcome is the safety of the anatomical right posterior sectionectomy performed IOUS-guided finger compression.	6 months

Secondary Outcome Measures

Name	Time	Method
The secondary outcome is the efficacy of the anatomical right posterior sectionectomy performed by IOUS-guided finger compression.	1 year

Trial Locations

Locations (1)

University of Milan School of Medicine, IRCCS Istituto Clinico Humanitas; 🇮🇹 Rozzano, Milan, Italy