MIrena coil to Reduce Endometrial Neoplastic Abnormalities

Not Applicable

• Conditions: Endometrial hyperplasia and endometrioid adenocarcinoma of the endometrium; Cancer

• Registration Number: ISRCTN31662931
• Lead Sponsor: Central Manchester University Hospitals NHS Trust (CMFT) (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-06-12
• Last Update Posted: 24 April 2023
• Study Completion: 2027-01-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: Female
• Target Recruitment: 150

Inclusion Criteria

1. Age 18 or more
2. Attending the gynaecological outpatient clinic at St Mary?s Hospital
3. Biopsy-proven well differentiated endometrioid adenocarcinoma of the endometrium (EC) with no myometrial invasion and/or endometrial hyperplasia (EH)
4. Clinical decision to treat EH or EC with progestins
5. Written, informed consent to take part in the study; Target Gender: Female

Exclusion Criteria

1. Non endometrioid or mixed histology or concerning histological features
2. Myometrial invasion on imaging
3. Progestin therapy contraindicated
4. Unable to sample endometrium pre/post progestin therapy

Study & Design

• Study Type: Interventional
• Study Design: Not specified