Effect of acyclovir nanofiber patch in treatment of recurrent herpes labialis

Phase 3

Recruiting

• Conditions: Recurrent herpes labialis.; Herpesviral vesicular dermatitis, Herpes simplex facialis, labialis; B00.1

• Registration Number: IRCT20141124020073N2
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 September 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Recurrent (secondary) and not primary lesions
Lesions in the vesicular stage (lesion size =1 cm)

Exclusion Criteria

Any allergy to acyclovir or the history of severe allergy to other drugs
Diagnosis of systemic diseases; liver or kidney disorders
Inherited or acquired immunodeficiency disease
Manipulations, such as scratching or shaving at the site
Use of birth control pills, pregnancy or lactation status
Use of antiviral, anti-inflammatory, steroidal, or analgesic drugs
Use of local agents, such as cosmetic products, lip lubricants, and sunscreen at the site of the lesion during treatment

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Symptoms of patient discomfort (pain, itching, burning sensation). Timepoint: Daily measurement of the symptoms from the beginning of treatment (baseline) until the symptoms disappeared. Method of measurement: Using a numerical scale, ranging from 0 to 10.;Crusting time. Timepoint: Patients follow-up on the second, forth and sixth days from the baseline. Method of measurement: Clinical examination.;Healing time. Timepoint: Patients follow-up on the second, forth and sixth days from the baseline. Method of measurement: Clinical examination.