OPEP Therapy in COPD/chronic bronchitis patients with excess mucus
Recruiting
- Conditions
- COPDchronic bronchitissputumairway clearanceCOPDchronische bronchitissputummucusklaring
- Registration Number
- NL-OMON27221
- Lead Sponsor
- Martini Hospital Groningen (department of Pulmonary Diseases)
- Brief Summary
not yet
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 96
Inclusion Criteria
Patients with COPD or bronchitis with excessive mucus will be included in this study.
Exclusion Criteria
Exclusion criteria
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint is the mean CCQ Total score after 3 months.
- Secondary Outcome Measures
Name Time Method The secondary endpoints at 3 months are:<br /><br>- mean subdomain scores of the CCQ, respectively symptoms, mental and functional state.<br /><br>- mean Leicester Cough Questionnaire (LCQ) total and domain scores.<br /> <br>- St. George’s Respiratory Questionnaire (SGRQ).<br /><br>- A global rating of change in health status and in ability of coughing up sputum after 3 months will be used to evaluate self-perceived change.<br /><br>- Lung function (spirometry, FEV1, FEV1%pred, FVC, FVC%pred).<br /><br>- Exacerbation rate.<br /><br>- Hospitalisation rate for COPD. <br>