The change of bacterial microbiome after using La Roche-Posay Effaclar Duo plus compared to retinoic acid 0.025% cream and benzoyl peroxide 2.5% gel in mild acne vulgaris

'Oreal Thailand0 个研究点目标入组 45 人开始时间: 2021年5月31日最近更新: 2024年8月19日

适应症

试验速览

Topical application of DC, VAA, or BP can significantly and differently modulate the skin microbiota in AV participants.

•1.Men or women with 18-45 years old at the time of screening
•2.Presence of minimum of 10 comedones and maximum of 5 inflammatory acne on the face
•3.Mild acne vulgaris defined as IGA 1 (Almost clear; rare noninflammatory lesions with more than one small inflammatory lesion) to IGA 2 (Mild severity; some inflammatory lesions with no more than a few inflammatory lesions (papules/pustules only, no nodular lesions)
•4.Subjects who are willing to use nonantibacterial bar soap for facial cleansing throughout the study
•5.Subjects who are informed in detail about the research study and express their interests in participation.
•6.Subjects must be able to comply with study protocol

•1.History of systemic or topical antibiotic use within 1 month prior to the baseline study visit
•2.Dermatologic procedural treatments within previous 6 months before study enrollment
•3.Systemic acne treatment within 4 weeks before study enrollment.
•4.Topical acne treatment within 2 weeks before study enrollment.
•5.Female subjects who have significant signs of hyperandrogenism or history of irregular menstrual cycles
•6.Female subjects who are currently in pregnancy or breastfeeding

发起方

'Oreal Thailand