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Clinical trial of adipose tissue-derived stem cell spheroids transplantation for knee osteoarthritis

Phase 1
Conditions
Knee osteoarthritis
Registration Number
JPRN-jRCTb050200097
Lead Sponsor
Sobajima Satoshi
Brief Summary

It was suggested that S-ADSCs transplantation for knee osteoarthritis in 5 patients has a certain level of safety. This study was conducted in a small number of cases, and more cases are needed to determine its efficacy. It was suggested.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
5
Inclusion Criteria

Patients with dysfunction associated with osteoarthritis
-Over 20 years old when obtaining consent
-No improvement in standard conservative therapy for insurance indication
-Don't wish to perform artificial joint replacement or osteotomy
-Obtain written consent sufficient explanation about this study
-Able to comply with a fixed schedule

Exclusion Criteria

-Patients who have difficulty with subcutaneous liposuction
-Patients with cancer
-Patients who are using anti-cancer drugs, biologics or immunosuppressants
-Patients with active infection
-Patients who have recieved this treatment within a month
-Patients with serious complicaitons such as heart disease, liver diseaes, lung disease, kidny disease, bleeding tendency, uncontroled diabetes, hypertension, etc.
-Patients with a history of drug sensitivity to anesthetics
-Other patients judged inappropriate by doctors

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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