NL-OMON53470招募中3 期
Rituximab Effect on Decreasing glUcoCorticoid Exposition in PolyMyalgia Rheumatica Patients Experiencing a PMR Relapse - REDUCE PMR 2
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 174
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Polymyalgia rheumatica diagnosis fullfilling the 2012 EULAR/ACR
- •classification criteria
- •Re-emerging PMR symptoms and elevated ESR or CRP levels
- •Unable to reduce glucocorticoid dose below 5mg/day prednisolone or
- •equivalent.
排除标准
- •Treatment with systemic immunosuppressants (other than GC, MTX, leflunomide
- •and azathioprine) 3 months prior to inclusion
- •(clinical) suspect concomitant giant cell arteritis or other rheumatic
- •inflammatory diseases;
- •concomitant conditions that might significantly interfere with PMR pain or
- •movement evaluation as judged by the investigator;
- •previous hypersensitivity for RTX or contra-indications to RTX.
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