ISRCTN18419796进行中（未招募）Unknown
Pulmonary vein isolation versus endo-epicardial linear ablation for persistent atrial fibrillation: a randomized multicentre trial.
niversity Hospitals Sussex NHS Foundation Trust0 个研究点目标入组 166 人开始时间: 2023年8月29日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 166
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Previous left atrial ablation with pulmonary vein isolation only
- •2. Indicated for repeat catheter ablation for documented symptomatic recurrent persistent AF
- •3. Aged > 18 years
- •4. Willing and able to provide informed consent
- •5. Willing and able to comply with the study requirements
排除标准
- •1. Pregnancy or planning pregnancy
- •2. Previous cardiac surgery
- •3. Previous pericarditis
- •4. Previous linear ablation in the LA
- •5. LA diameter > 55 mm in TTE
- •6. Current involvement in another interventional clinical trial
- •7. Contraindication to anticoagulation
- •8. Longstanding persistent AF lasting more than 2 years in duration
- •9. Cyanotic congenital heart disease
- •10. Body Mass Index > 40
- •11. Unable to use a smartphone with the ‘myMerlin’ application
- •12. Failure to achieve sinus rhythm, despite a maximum of 4x cardioversions +/- IV antiarrhythmic drugs
- •13. Failure to achieve epicardial access, via the CO2 insufflation technique
- •14. Re-assessment of PVI after the 20-minute waiting period
- •15. Implantable cardiac monitor permanently explanted, during the blanking period
研究者
相似试验
已完成
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进行中（未招募）
1 期
Continuing versus stopping heart rhythm medication after an operation restoring your normal heart rhythm in patients with a heart rhythm disorder: a study across multiple hospitals.Symptomatic persistent atrial fibrillation: atrial fibrillation, that lasts longer than 7 days, including episodes that are terminated by cardioversion, either with drugs or by direct current cardioversion, after 7 days or more. Episodes of atrial fibrillation have to be accompanied by symptoms.MedDRA version: 20.0Level: LLTClassification code 10071667Term: Persistent atrial fibrillationSystem Organ Class: 100000004849EUCTR2018-002103-33-DKAZ Sint-Jan Brugge-Oostende AV220
进行中（未招募）
1 期
Continuing versus stopping heart rhythm medication after an operation restoring your normal heart rhythm in patients with a heart rhythm disorder: a study across multiple hospitals.Symptomatic persistent atrial fibrillation: atrial fibrillation, that lasts longer than 7 days, including episodes that are terminated by cardioversion, either with drugs or by direct current cardioversion, after 7 days or more. Episodes of atrial fibrillation have to be accompanied by symptoms.MedDRA version: 20.0 Level: LLT Classification code 10071667 Term: Persistent atrial fibrillation System Organ Class: 100000004849EUCTR2018-002103-33-ESAZ Sint-Jan Brugge-Oostende AV220
进行中（未招募）
1 期
Continuing versus stopping heart rhythm medication after an operation restoring your normal heart rhythm in patients with a heart rhythm disorder: a study across multiple hospitals.Symptomatic persistent atrial fibrillation: atrial fibrillation, that lasts longer than 7 days, including episodes that are terminated by cardioversion, either with drugs or by direct current cardioversion, after 7 days or more. Episodes of atrial fibrillation have to be accompanied by symptoms.MedDRA version: 20.0 Level: LLT Classification code 10071667 Term: Persistent atrial fibrillation System Organ Class: 100000004849EUCTR2018-002103-33-FRAZ Sint-Jan Brugge-Oostende AV220
进行中（未招募）
1 期
Continuing versus stopping heart rhythm medication after an operation restoring your normal heart rhythm in patients with a heart rhythm disorder: a study across multiple hospitals.Symptomatic persistent atrial fibrillation: atrial fibrillation, that lasts longer than 7 days, including episodes that are terminated by cardioversion, either with drugs or by direct current cardioversion, after 7 days or more. Episodes of atrial fibrillation have to be accompanied by symptoms.MedDRA version: 20.0 Level: LLT Classification code 10071667 Term: Persistent atrial fibrillation System Organ Class: 100000004849EUCTR2018-002103-33-ATAZ Sint-Jan Brugge-Oostende AV220