Effects of Endurance Training under Normobaric, Hypoxic Conditions on Fatigue inPatients with Multiple Sclerosis: Results of a Randomized, Prospective Pilot Study.

Not Applicable

• Conditions: G35; Multiple sclerosis

• Registration Number: DRKS00006307
• Lead Sponsor: eurologisches Rehabilitationszentrum Quellenhof Bad Wildbad

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2008-09-30
• Study Start: 2014-07-17
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 39

Inclusion Criteria

patients over 18 years of age
MS according to the McDonald
criteria [19] chronic progressive or relapsing-remitting MS with walking ability
(EDSS = 6) and self-reported fatigue
Written informed
consent

Exclusion Criteria

Patients with severe cardiopulmonary disease
glucocorticosteroid therapy within the previous 30 days,
serious functional limitations (i.e. high spasticity of the legs) limiting the ability to use the
cycle ergometer as well as severe cognitive deficits that would have made it impossible
to understand directions

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
fatigue: questionnaire: Würzburger Erschöpfungsinventar Multiple Sklerose (WEIMuS). Baseline, 7th and 14th day after baseline.

Secondary Outcome Measures

Name	Time	Method
Endurance capacity: 6 minute walk test recorded at baseline and 14th day after baseline.