Effect of dexmeditomidine with combination of bupivacaine in paediatric caudal anaesthesia

Phase 2

Not yet recruiting

• Conditions: Other intraoperative and postprocedural complications and disorders of genitourinary system, (2) ICD-10 Condition: N998||Other intraoperative and postprocedural complications and disorders of genitourinary system,

• Registration Number: CTRI/2023/08/057050
• Lead Sponsor: Jawaharlal Nehru Medical College

Brief Summary

Caudal epidural block is one of the most common regional techniques in paediatric anesthesia .Caudal block is a safe and reliable technique, easy to perform and has been foundto be very effective in children,we will conduct this study to compare two different dosages, 1μg/kg dexmedetomidine with bupivacaine during caudal epidural block which has been proved to increase analgesia duration in comparison with 0.5μg/kg dexmedetomidine as an adjuvant for duration of postoperative analgesia ,hemodynamic changes and adverse effects.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-08-27
• Study Start: 2023-09-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Age group of 6 months to 6 years ASA Class I & II patients.
• Children posted for infraumbilical surgeries.

Exclusion Criteria

• ASA grade 3, 4 and 5.
• allergy to any of the study drug Cardiac, Respiratory diseases Hepatic, Renal dysfunction developmental delay or mental retardation Infection at the site of caudal block.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Caudal dexmeditomidine (1mcg/kg) with 0.25% bupivacaine for paediatric infra umbilical surgeries achieved significant post operative pain relief compared to caudal dexmeditomidine (0.5mcg/kg) with 0.25% bupivacaine.	240 minutes

Secondary Outcome Measures

Name	Time	Method
Incidence of side effects was less in 0.5 mcg/kg dexmeditomidine group when compared to 1mcg/kg group	240 minutes

Trial Locations

Locations (1)

Jawaharlal Nehru Medical College; 🇮🇳 Wardha, MAHARASHTRA, India

Jawaharlal Nehru Medical College

🇮🇳Wardha, MAHARASHTRA, India

BGeetha Sindhuja

Principal investigator

9492659773

sindhugeetha8@gmail.com