Comparison of two different dosage of dexmeditomidine with bupivacaine in paediatric caudal Anaesthesia for infraumbilical surgeries
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Caudal dexmeditomidine (1mcg/kg) with 0.25% bupivacaine for paediatric infra umbilical surgeries achieved significant post operative pain relief compared to caudal dexmeditomidine (0.5mcg/kg) with 0.25% bupivacaine.
研究概览
简要总结
Caudal epidural block is one of the most common regional techniques in paediatric anesthesia .Caudal block is a safe and reliable technique, easy to perform and has been foundto be very effective in children,we will conduct this study to compare two different dosages, 1μg/kg dexmedetomidine with bupivacaine during caudal epidural block which has been proved to increase analgesia duration in comparison with 0.5μg/kg dexmedetomidine as an adjuvant for duration of postoperative analgesia ,hemodynamic changes and adverse effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 6.00 Month(s) 至 6.00 Year(s)（—）
- 性别
- All
入选标准
- •Age group of 6 months to 6 years ASA Class I & II patients.
- •Children posted for infraumbilical surgeries.
排除标准
- •ASA grade 3, 4 and
- •allergy to any of the study drug Cardiac, Respiratory diseases Hepatic, Renal dysfunction developmental delay or mental retardation Infection at the site of caudal block.
结局指标
主要结局
Caudal dexmeditomidine (1mcg/kg) with 0.25% bupivacaine for paediatric infra umbilical surgeries achieved significant post operative pain relief compared to caudal dexmeditomidine (0.5mcg/kg) with 0.25% bupivacaine.
时间窗: 240 minutes
次要结局
- Incidence of side effects was less in 0.5 mcg/kg dexmeditomidine group when compared to 1mcg/kg group(240 minutes)