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临床试验/NCT00646256
NCT00646256Unknown不适用

Psychoeducation in Patients With Schizophrenia: Neuropsychological Performance and Cognitive Training as Determinants of Outcome

German Research Foundation2 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2006年2月最近更新:
适应症

试验速览

阶段
不适用
入组人数
120
试验地点
2
主要终点
illness knowledge, adherence to treatment, insight to the illness, satisfaction with treatment. 9-month follow-up: number of rehospitalizations, days in hospital

研究概览

简要总结

The aim of the study is to examine whether the efficacy of psychoeducation in patients with schizophrenia or schizoaffective disorders is dependent on their cognitive performance level and if a preceding cognitive training can enhance the therapeutic effects of psychoeducation

详细描述

Schizophrenic inpatients are examined shortly after admission with a broad battery of clinical and neurological rating scales and neuropsychological tests. They are then randomized to either standard treatment (including antipsychotic medications, art and occupational therapy, psychotherapy) or to standard treatment plus daily computerbased cognitive training (COGPACK; ten 1-hour sessions over two weeks). After repetition of the broad assessment battery all patients (and some of their family members) take part in a bifocal psychoeducation group program (eight 1-hour sessions over four weeks). Specific pre-post measures are illness knowledge, self and expert ratings of adherence to treatment, insight to the illness, treatment satisfaction. The study also includes a 9-month follow-up, with number of rehospitalizations, days in hospital and psychopathology as the primary outcome measures.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Inpatients
  • Informed consent
  • German as first language or very good knowledge of German

排除标准

  • Mental retardation
  • Any serious somatic illness

结局指标

主要结局

illness knowledge, adherence to treatment, insight to the illness, satisfaction with treatment. 9-month follow-up: number of rehospitalizations, days in hospital

时间窗: Baseline, after cognitive training, after psychoeducation, 9-month after end of psychoeducation

次要结局

  • Psychopathological status
  • Psychosocial rehabilitation

研究者

申办方类型
Other

研究点 (2)

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