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Clinical Trials/NCT00646256
NCT00646256
Unknown
N/A

Psychoeducation in Patients With Schizophrenia: Neuropsychological Performance and Cognitive Training as Determinants of Outcome

German Research Foundation1 site in 1 country120 target enrollmentFebruary 2006

Overview

Phase
N/A
Intervention
Not specified
Conditions
Schizophrenia
Sponsor
German Research Foundation
Enrollment
120
Locations
1
Primary Endpoint
illness knowledge, adherence to treatment, insight to the illness, satisfaction with treatment. 9-month follow-up: number of rehospitalizations, days in hospital
Last Updated
18 years ago

Overview

Brief Summary

The aim of the study is to examine whether the efficacy of psychoeducation in patients with schizophrenia or schizoaffective disorders is dependent on their cognitive performance level and if a preceding cognitive training can enhance the therapeutic effects of psychoeducation

Detailed Description

Schizophrenic inpatients are examined shortly after admission with a broad battery of clinical and neurological rating scales and neuropsychological tests. They are then randomized to either standard treatment (including antipsychotic medications, art and occupational therapy, psychotherapy) or to standard treatment plus daily computerbased cognitive training (COGPACK; ten 1-hour sessions over two weeks). After repetition of the broad assessment battery all patients (and some of their family members) take part in a bifocal psychoeducation group program (eight 1-hour sessions over four weeks). Specific pre-post measures are illness knowledge, self and expert ratings of adherence to treatment, insight to the illness, treatment satisfaction. The study also includes a 9-month follow-up, with number of rehospitalizations, days in hospital and psychopathology as the primary outcome measures.

Registry
clinicaltrials.gov
Start Date
February 2006
End Date
December 2008
Last Updated
18 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Inpatients
  • Informed consent
  • German as first language or very good knowledge of German

Exclusion Criteria

  • Mental retardation
  • Any serious somatic illness

Outcomes

Primary Outcomes

illness knowledge, adherence to treatment, insight to the illness, satisfaction with treatment. 9-month follow-up: number of rehospitalizations, days in hospital

Time Frame: Baseline, after cognitive training, after psychoeducation, 9-month after end of psychoeducation

Secondary Outcomes

  • Psychopathological status
  • Psychosocial rehabilitation

Study Sites (1)

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