Cognitive Determinants of Psychoeducation and Information in Psychoses

Not Applicable

• Conditions: Schizophrenia; Delusional Disorders (ICD-10)
• Interventions: Behavioral: COGPACK training, psychoeducation

• Registration Number: NCT00646256
• Lead Sponsor: German Research Foundation

Brief Summary

The aim of the study is to examine whether the efficacy of psychoeducation in patients with schizophrenia or schizoaffective disorders is dependent on their cognitive performance level and if a preceding cognitive training can enhance the therapeutic effects of psychoeducation

Detailed Description

Schizophrenic inpatients are examined shortly after admission with a broad battery of clinical and neurological rating scales and neuropsychological tests. They are then randomized to either standard treatment (including antipsychotic medications, art and occupational therapy, psychotherapy) or to standard treatment plus daily computerbased cognitive training (COGPACK; ten 1-hour sessions over two weeks). After repetition of the broad assessment battery all patients (and some of their family members) take part in a bifocal psychoeducation group program (eight 1-hour sessions over four weeks). Specific pre-post measures are illness knowledge, self and expert ratings of adherence to treatment, insight to the illness, treatment satisfaction. The study also includes a 9-month follow-up, with number of rehospitalizations, days in hospital and psychopathology as the primary outcome measures.

Study Timeline

• Study Start: 2006-02
• Status Verified: 2008-03
• Study First Submitted: 2008-03-25
• Study First Submitted QC: 2008-03-25
• Last Update Submitted: 2008-03-25
• Study First Posted: 2008-03-28
• Last Update Posted: 2008-03-28
• Primary Completion: 2008-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Inpatients
• Informed consent
• German as first language or very good knowledge of German

Exclusion Criteria

• Mental retardation
• Any serious somatic illness

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
COGPACK training	COGPACK training, psychoeducation	-

Primary Outcome Measures

Name	Time	Method
illness knowledge, adherence to treatment, insight to the illness, satisfaction with treatment. 9-month follow-up: number of rehospitalizations, days in hospital	Baseline, after cognitive training, after psychoeducation, 9-month after end of psychoeducation

Secondary Outcome Measures

Name	Time	Method
Psychopathological status
Psychosocial rehabilitation

Trial Locations

Locations (1)

Klinik und Poliklinik für Psychiatrie und Psychotherapie, Klinikum rechts der Isar, Technical University of Munich; 🇩🇪 Munich, Germany