MedPath

COVID-19 Tests With Saliva Specimens

Not Applicable
Conditions
Covid19
Interventions
Other: Saliva collection
Registration Number
NCT04567953
Lead Sponsor
Paradigm Laboratories LLC
Brief Summary

Upper respiratory swabs, such as the nasopharyngeal (NP) swab, have so far been major specimen sources used for the SARS-COV-2 molecular test. However, due to the discomfort and invasiveness of NP collection, and the expense of personal protective equipment, alternative sampling sources such as saliva are desired. The purpose of this proposed study is: 1) to examine whether saliva can be used as an specimen for the SARS-COV-2 molecular test; 2) to test if gingival crevicular fluids is a reliable specimen for the SARS-COV-2 antibodies.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
2000
Inclusion Criteria
  • Persons referred for COVID-19 testing including those with COVID-19 symptoms and/or a suspected SARS-COV-2 infection or undergoing surveillance testing and

    • Is able to give informed consent
    • Is able to understand oral or written instructions, and
    • Is able to mentally and physically perform self-collection of saliva using the provided collection device.
Exclusion Criteria
    • Adults unable to consent
  • Individuals who are not yet adults (infants, children, teenagers)
  • Employees of Paradigm lab and the assisted living facilities involved in the study
  • Members of other vulnerable populations

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Saliva and NP paired specimen collectionSaliva collection-
Primary Outcome Measures
NameTimeMethod
The clinical evaluation of saliva as specimen for COVID-19 molecular test1 hour

We will evaluate the positive and negative agreement of saliva with nasopharyngeal swab as specimens for COVID-19 molecular test.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Paradigm Laboratories

🇺🇸

Tucson, Arizona, United States

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