Comparison of silver diamine fluoride and fluoride varnish on caries prevention in patient with head and neck radiation therapy

Phase 2

• Conditions: - new caries according to international caries detection and assessment system (ICDAS)- new caries according to Decayed, Missing, and Filled Surfaces (DMFS) index - new caries according to Decayed, Missing, and Filled Teeth (DMFT) index; radiation caries; prevention; SDF; NaF; head and neck radiotherapy

• Registration Number: TCTR20230826001
• Lead Sponsor: S.D. Tantavade 1988 Co.,Ltd.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 96

Inclusion Criteria

Head and neck cancer patients who have completed radiotherapy more than 1 month and within 3 months
- Age 18 year or more
- Complete dental treatment before study enrollment
- Have at least 5 teeth

Exclusion Criteria

- Incapable of dental evaluation due to limited mouth opening
- Allergic to silver
- Presence of oral mucositis
- Received head and neck radiation more than 1 course
- Using fluoride mouth rinse

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Radiation caries 2 years international caries detection and assessment system (ICDAS) index

Secondary Outcome Measures

Name	Time	Method
caries 2 years Decayed, Missing, and Filled Surfaces (DMFS) index ,caries 2 years Decayed, Missing, and Filled Teeth (DMFT) index