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临床试验/CTRI/2021/07/034716
CTRI/2021/07/034716尚未招募Phase 3 4

A COMPARATIVE CLINICAL STUDY OF CHATUHA PRASRATIKA BASTI AND SATAVARI KSIRA PAKA IN THE MANEGMENT OF KSHINA SHUKRA WSR TO OLIGOZOOSPERMIA

Dr Sarvepalli Radhakrishnan Rajasthan Ayurveda University Jodhpur1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2021年7月28日最近更新:

试验速览

阶段
Phase 3 4
状态
尚未招募
发起方
入组人数
50
试验地点
1
主要终点
THE SCORING SYSTEM DEVELOPED BY MEHRA AND SINGH(1995) WAS ADOPTED

研究概览

简要总结

Kshina Shukra is one among the Astavidha Shukra dushti, in which qualitative as well quantitative vitiation of Shukra dhatu occur. While describing the dushti associted with Shukra and Artava, Vagbhatacharya explained Kshina Shukra as a pathological condition caused by vitiated Vata and Pitta. Khsina Shukra somewhat resembles Oligozoospermia. Oligozoospermia also a disease of male reproductive system, in which there is quantitative reduction of the count of spermatozoa (<20million / ml). Kshina Shukra and Oligozoospermia conditions are not exactly same, but Oligozoospermia indicates quantitative vitiation of Shukra Dhatu (Kshina Shukra). In Allopathy various drugs like Testosterone, Clomiphene Citrate 25 mg orally etc. are being used to increase sperm count, However these drugs are expensive and producing several Adverse Effects like head-ache, blurred vision, stroke, seizure, shortness of breath, decreased testicular size, so we looking to alternative system especially Ayurveda and find out solution to increase sperm count motility and volume simultaneously. The study is open labelled parallel group trial to prove the efficacy of Chatuha Prasratika Basti and Satavari Kshira Paka (internally) in the management of Kshina Shukra w.s.r to Oligospermia. In one group, 25 patients will be administered with Chatuha Prasratika Basti for 15 days, next 25 patients will be administered with satavari kshira paka for 30 days.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
25.00 Year(s) 至 50.00 Year(s)(—)
性别
Male

入选标准

  • 1.Patient with classical symptoms of kshina shukra 2.Patient should not take any other medicine for kshina shukra 3.Patient who are basti yogya.

排除标准

  • 1.Sperm count above 20 million 2.Patients of azoospermia and aspermia 3.All congenital case of impotency 4.Necrospermia 5.Patient who had undergone surgical procedure for hydrocele varicocele etc 6.Patients suffering with STD, DM, TB, Typhoid ,Mallignancy 7.Any other conditions in which basthi is contraindicated.

结局指标

主要结局

THE SCORING SYSTEM DEVELOPED BY MEHRA AND SINGH(1995) WAS ADOPTED

时间窗: 45 Days

SUBJECTIVE CRITERIA

时间窗: 45 Days

OBJECTIVE CRITERIA

时间窗: 45 Days

SIGNS OF SAMYAK BASTHI KARMA

时间窗: 45 Days

SEMINAL ANALYSIS

时间窗: 45 Days

次要结局

  • To find out the comparative efficacy of the treatment in both groups WITH THE HELP OF SCORING SYSTEM DEVELOPED BY MEHRA AND SINGH (1995), SIGNS OF SAMYAK BASTHI KARMA AND SEMINAL ANALYSIS(45 days)

研究者

发起方
Dr Sarvepalli Radhakrishnan Rajasthan Ayurveda University Jodhpur
申办方类型
Government medical college

研究点 (1)

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