A Prospective, Randomized, Double-Blind Comparative Study of the Hemodynamic Response to Intravenous Dexmedetomidine Versus Lignocaine During Endotracheal Intubation
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare the haemodynamic changes during laryngoscope and endotracheal intubation with intravenous dexmedetomidine versus lignocaine from baseline
研究概览
简要总结
This thesis investigates and compares the effectiveness of two drugs—dexmedetomidine and lignocaine—in controlling the hemodynamic (heart rate and blood pressure) responses caused by endotracheal intubation, a common procedure during general anesthesia. Endotracheal intubation can lead to a significant stress response, which may be harmful in certain patients. The study involved administering either dexmedetomidine or lignocaine intravenously to patients before intubation and monitoring their cardiovascular responses. The findings suggest which of the two drugs is more effective in blunting the rise in heart rate and blood pressure, offering safer anesthesia management during surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA I & II, age 18-55 yrs.
排除标准
- •Patients sensitive or allergic to drug,obese patient and with predicted difficult airway, and not willing to participate in study.
结局指标
主要结局
To compare the haemodynamic changes during laryngoscope and endotracheal intubation with intravenous dexmedetomidine versus lignocaine from baseline
时间窗: To compare the haemodynamic changes during laryngoscope and endotracheal intubation with intravenous dexmedetomidine versus lignocaine from baseline
次要结局
- Any adverse effect of dexmedetomidine & lignocaine such as hypotension, bradycardia, respiratory depression from baseline(Any adverse effect of dexmedetomidine & lignocaine such as hypotension, bradycardia, respiratory depression)
研究者
Dr Veena Mathur
JLNMC AJMER