Preoxygenation with Pressure Support Ventilation (PSV) mode versus high flow oxygen with Zero End Expiratory Pressure (ZEEP) on end tidal Oxygen in rapid sequence intubation (RSI).

Rapid Sequence Intubation is a procedure that aims to reduce the incidence of pulmonary aspiration during airway management. Rapid Sequence Intubation is performed by administering an induction agent followed by a neuromuscular blocker. Rapid sequence intubation secures the airway, minimizing the risk of aspiration and facilitating intubation in critically ill patients. Effective preoxygenation is essential for enhancing oxygen reserves and boosting functional residual capacity. There are different techniques employed in the administration of preoxygenation which include breathing 100percent Oxygen at normal tidal volume for 3 to 5 minutes and taking eight vital capacity breaths in 1 minute. A newer technique that is helpful for better preoxygenation is Non Invasive Ventilation with the Pressure Support Ventilation technique. Patients posted for laparoscopic surgery will be recruited for the study. Patients who consent to the study will be randomized using computer generated randomization to allocate each patient into the Interventional group which is group A and the Control group that is group B. Patients in group A will receive preoxygenation using pressure support ventilation mode set at 2 cm H2O with a PEEP of zero. Conversely in group B preoxygenation will be given with 100percent high flow oxygen for 3 minutes. Before the preoxygenation procedure the patient will undergo the collection of one arterial blood gas and one venous blood gas while breathing room air. Following the preoxygenation an additional venous blood gas will be collected after intubation. Adequacy of oxygenation will be compared using PaO2 values from the collected samples. Appropriate descriptive and analytical statistics will be used to establish the study objectives.