High (180 ml/kg) versus standard (150 to 160 ml/kg) volume feeding among preterm very low birth weight infants in a tertiary level SNCU - A randomized controlled trial.
概览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- Department of pediatrics Guru Gobind Singh medical college and hospital Faridkot
- 入组人数
- 104
- 试验地点
- 1
- 主要终点
- To compare the growth velocity weight in gram per kg per day in very low birth weight neonates fed with standard versus high volume feeds.
概览
简要总结
Postnatal growth of very low birth weight neonates is a very important aspect of their management. Prevalence of postnatal growth restriction in preterm as well as low birth weight neonates is quite high at time of discharge and matter of concern. A metanalysis of studies comparing high versus standard volume enteral feeds in preterm and low birth weight infants conducted in 2021 concluded that high volume feeds, more than 180 ml per kg improve weight gain during hospital stay. The available data were inadequate to compare other anthropometric parameters or adverse outcomes in preterm very low birth weight fed with high volume versus standard volume enteral feeds. They concluded that further studies are needed on the subject. Therefore, we planned this randomized controlled trial to compare study high volume versus standard volume feeds in very low birth weight infants.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 1.00 Day(s) 至 28.00 Day(s)（—）
- 性别
- All
入选标准
- •Preterm neonates having birth weight less than or equal to 1500gm with postnatal age less than 14 days Both inborn and out-born neonates will be enrolled Baby should be hemodynamically stable and have achieved feeding volume of at least 100ml/kg/day.
排除标准
- •Hemodynamically significant patent duct arteriosus.
- •Any Necrotizing enterocolitis at admission.
- •Known Congenital neuro-malformations or gastrointestinal malformation Suspected Chromosomal anomalies.
- •Refusal of consent.
结局指标
主要结局
To compare the growth velocity weight in gram per kg per day in very low birth weight neonates fed with standard versus high volume feeds.
时间窗: weight will be measured daily and weekly weight gain will be measured
次要结局
- To compare the other anthropometric measures viz length & head(circumference, & postnatal growth failure among these two groups.)
研究者
Sunpreet Kaur
Guru Gobind Singh Medical college and hospital faridkot , Punjab