Observational Study of Oxygen Delivery During a Fractional Fluid Expansion
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Measurement of oxygen delivery
研究概览
简要总结
Fluid expansion during cardiocirculatory insufficiency was helped by cardiac output monitoring. However, the goal of fluid expansion was to increase the oxygen delivery, which consider cardiac output, but also Haemoglobin which decrease during a fluid challenge. The maximalization of cardiac output could decrease the oxygen delivery if the haemodilution was too wide. The aim of this study was to describe the oxygen delivery during a fluid expansion conducted for cardiac output maximalization, following actual guidelines.
详细描述
One group of 20 anticipated patients
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults over 18 years
- •Patients in intensive care after cardiac surgery under mechanically ventilation and with oesophageal Doppler
排除标准
- •Arrythmia
- •Pregnancy or childrens
- •Patients without cardiac output monitoring with oesophageal Doppler
- •Patients without medical indication for fluid expansion
- •Urgency surgery
研究组 & 干预措施
Hypovolemia
Fluid expansion
干预措施: hydroxyethylstarch 130/0.4 (Drug)
结局指标
主要结局
Measurement of oxygen delivery
时间窗: only during the fluid challenge
Retrospective calculation of oxygen delivery (ml.min.m-2)during a fractional fluid expansion every 100ml of hydroxyethyl starch until cardiac output maximalization with oesophageal Doppler and arterial gazes (for PaO2 and Haemoglobin)from arterial line.
次要结局
- Study of central venous saturation(only during the fluid challenge)
研究者
Marc-Olivier FISCHER
Medecine Doctor
University Hospital, Caen