Panniculitis in Dermatomyositis
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Determine the clinical and histological characteristics of panniculitis in dermatomyositis
研究概览
简要总结
Adipose tissue involvement is rare in dermatomyositis. The occurrence of partial or diffuse lipodystrophy is a rare but well-characterized manifestation, particularly in juvenile forms of dermatomyositis. Panniculitis, on the other hand, is exceptional and rarely described in the literature, mostly in the form of clinical cases.
Panniculitis in dermatomyositis is exceptional. There are no validated diagnostic criteria or treatment recommendations. Treatment is based, by analogy, on the therapeutic strategy for lupus panniculitis and involves synthetic antimalarials combined with steroids and/or immunosuppressants.
The aim of this study is to describe panniculitis in dermatomyositis in order to determine whether there are clinical or histological characteristics that distinguish it from other causes of panniculitis, particularly panniculitis associated with lupus erythematosus.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 1 Year 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subject aged 1 year and older
- •With a confirmed diagnosis of dermatomyositis
- •With a confirmed diagnosis of panniculitis
排除标准
- •Panniculitis for which another cause has been established, particularly infectious and metabolic panniculitis
结局指标
主要结局
Determine the clinical and histological characteristics of panniculitis in dermatomyositis
时间窗: Up to 30 months
The investigators aim to describe: how inflammation of the subcutaneous fat manifests * in individuals with dermatomyositis * both: * clinically and visually in the patient * under the microscope (histology)
次要结局
未报告次要终点