Temporal Trends in Transfusion Strategies and Outcomes in Trauma: A 5-Year Analysis From a Level I Trauma Center

Mariah Arif1 个研究点分布在 1 个国家目标入组 137 人开始时间: 2020年1月1日最近更新: 2026年5月22日

试验速览

阶段: 不适用
状态: 已完成
发起方
入组人数: 137
试验地点: 1

研究概览研究设计入排标准研究者研究点记录与标识符相似试验

研究概览

简要总结

This retrospective cohort study evaluated transfusion practices and outcomes in 137 severely injured trauma patients requiring massive transfusion at a Level I trauma center (2020-2025). This study analyzed balanced transfusion ratios, whole blood (WB) use, thromboelastography (TEG), and adjunctive hemostatic therapies to determine their impact on 30-day mortality and other clinical outcomes.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Retrospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Adult trauma patients (≥18 years) presenting directly to the trauma center were eligible for inclusion if they met at least one of the following criteria:
•Injury Severity Score (ISS) ≥16, or
•requirement for massive transfusion, defined as >10 units of packed red blood cells (PRBC) within the first 24 hours.

排除标准

•Death on arrival,
•Transfer from external institutions after initial resuscitation
•Incomplete transfusion or outcome data
•Significant pre-existing comorbidities (including advanced heart failure, end-stage renal disease, cirrhosis with portal hypertension, chronic oxygen dependence, or non-reversible anticoagulation therapy).
•Patients with isolated minor injuries not requiring trauma team activation were also excluded.

研究者

发起方

Mariah Arif

申办方类型

Other Gov

责任方

Sponsor Investigator

主要研究者

Mariah Arif

Principal Investigator

Hamad General Hospital

研究点 (1)

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