the Comparison of Voice Quality in Early Laryngeal Cancer Between Surgery and Radiotherapy

Phase 3

• Conditions: Voice Quality
• Interventions: Radiation: radiotherapy; Procedure: surgery

• Registration Number: NCT00497588
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

early laryngeal cancer is a well known field with great controversy in treatment. two options are available in treatment of patients the first one is partial laryngectomy and the second one is radiotherapy.one of major concern of patients have been the quality of voice ,so we design this trial to answer the priority of each options.

Detailed Description

early laryngeal cancer is a well known field with great controversy in treatment. two options are available in treatment of patients the first one is partial laryngectomy and the second one is radiotherapy.one of major concern of patients have been the quality of voice as part of quality of life ,so we design this clinical randomised trial to answer the priority of each options.

Study Timeline

• Study Start: 2007-03
• Study First Submitted: 2007-07-04
• Study First Submitted QC: 2007-07-05
• Study First Posted: 2007-07-06
• Status Verified: 2013-07
• Last Update Submitted: 2013-07-10
• Last Update Posted: 2013-07-11
• Primary Completion: 2014-04
• Study Completion: 2014-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 33

Inclusion Criteria

• Early laryngeal cancer

Exclusion Criteria

• No history of radiotherapy and collagen vascular disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
radiotherapy	radiotherapy	patients receive radiotherapy
surgery	surgery	Patients undergo surgery

Primary Outcome Measures

Name	Time	Method
quality of voice	3 to 6 month after therapy

Secondary Outcome Measures

Name	Time	Method
quality of life	6 month later

Trial Locations

Locations (1)

Imam Khomainee hospital; 🇮🇷 Tehran, Iran, Islamic Republic of