A study to see if the medication Ketamine can relieve depression in people who have not responded to another class of medication called Selective Serotonin Re-uptake Inhibitors (SSRIs)
- Conditions
- DepressionMedDRA version: 14.0Level: PTClassification code 10012378Term: DepressionSystem Organ Class: 10037175 - Psychiatric disordersTherapeutic area: Psychiatry and Psychology [F] - Mental Disorders [F03]
- Registration Number
- EUCTR2011-003654-40-IE
- Lead Sponsor
- Department of Psychiatry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 20
•Be able to give written informed consent,
•Be between the ages of 18 and 65 years of age, male or female
•DSM-IV major depression with a Hamilton depression score greater than 17
•Failed trial of an SSRI antidepressant at an adequate dose for at least 6 weeks duration
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 20
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
•Are less than 18 and greater than 65 years of age,
•Have a significant acute or chronic coexisting illness [cardiovascular, gastrointestinal, immunological, or any condition which contraindicates, in the investigators judgement, entry to the study].
•Having a condition or taking a medication that the investigator believes would interfere with the objectives of the study, pose a safety risk or confound the interpretation of the study results; to include, anti-inflammatory medications to include aspirin and steroids.
•Have evidence of immunodeficiency; bleeding disorder or coagulopathy.
•Pregnancy
•Family or Personal history of psychosis
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method